Cognition Support provides a blend of herbs with GinkgoSelect (ginkgo) supporting memory and Korean ginseng maintaining cognitive function. BacoMind (brahmi) supports memory recall and supports information processing in ageing individuals. Alpha lipoic acid helps to reduce free radicals formed in the body as well as supports energy production. Korean ginseng also relieves fatigue and supports physical stamina.

• Bacopa monnieri (brahmi) whole plant - BacoMind 200 mg (min. equiv. to dry 4 g, equiv. to bacosides A 90 mg)
• Ginkgo biloba (ginkgo) leaf - GinkgoSelect 60 mg (min. equiv. to dry 3 g, std. to ginkgo flavonglycosides 16 mg, std. to ginkgolides and bilobalide C5 4 mg)
• Panax ginseng (Korean ginseng) root 70.83 mg (min. equiv. to dry 212.5 mg, std. to ginsenosides Rg1, Re, Rf, Rg2, Rb1, Rb2, Rc, Rd 4.25 mg)
• Alpha lipoic acid (R,S form) 300 mg

Adults: Take 1 tablet three times a day, or as professionally prescribed. Take with food.

Do not use during pregnancy and breastfeeding.

Insufficient evidence is available to confirm the safety of Bacopa monnieri during pregnancy and lactation.

Insufficient evidence is available to confirm the safety of Ginkgo biloba during pregnancy and lactation.

Insufficient evidence is available to confirm the safety of Panax ginseng during pregnancy and lactation.

Ginkgo biloba may exert platelet-activating factor antagonist activity and theoretically enhance the effects of platelet inhibitor drugs, increasing the risk of bruising or bleeding. Use with caution when combining with anticoagulant/antiplatelet drugs.

It is recommended to discontinue use one week prior to surgery due to the potential platelet-aggregation inhibition activity of Ginkgo biloba.

Panax ginseng contains glycosides similar in structure to digoxin, which may interfere with some digoxin assay results.

Panax ginseng should not be taken concurrently with other stimulants including caffeine, due to a theoretical additive stimulant effect.

Theoretically, concomitant use of alpha lipoic acid with hypoglycaemic medication may affect glucose control. Observe patient.

Avoid combination -

Ginkgo biloba: Sodium aescinate - Adrenergic stimulants, vasopressor agents

Adverse event due to a likely interaction between sodium aescinate and ginkgo biloba extract: a case report.

Caution -

Ginkgo biloba: Anticoagulants, antithrombotics

No alteration in platelet function or coagulation induced by EGb761 in a controlled study

Influence of a 7-day treatment with Ginkgo biloba special extract EGb 761 on bleeding time and coagulation: a randomized, placebo-controlled, double-blind study in healthy volunteers

Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects

Inhibition of platelet activating factor (PAF)-induced aggregation of human thrombocytes by ginkgolides: considerations on possible bleeding complications after oral intake of Ginkgo biloba extracts

Bleeding complications precipitated by unrecognized Gingko biloba use after liver transplantation.

Fatal intracerebral mass bleeding associated with Ginkgo biloba and ibuprofen

Ginkgo biloba: CYP2C9 substrates

Ginkgo biloba: evaluation of CYP2C9 drug interactions in vitro and in vivo

Ginkgo biloba: Hypoglycaemic agents

Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects.

The effect of 3-month ingestion of Ginkgo biloba extract on Pancreatic b-cell function in response to glucose loading in normal glucose tolerant individuals

Ginkgo biloba: Substrates of multiple CYP enzyme subtypes

Induction and recovery of hepatic drug metabolizing enzymes in rats treated with Ginkgo biloba extract

Inhibition of human P450 enzymes by multiple constituents of the Ginkgo biloba extract

Influence of the Ginkgo extract EGb 761 on rat liver cytochrome P450 and steroid metabolism and excretion in rats and man

Analysis of the Inhibitory Potential of Ginkgo biloba, Echinacea purpurea and Serenoa repens on the Metabolic Activity of Cytochrome P450 3A4, 2D6 and 2C9

Ginkgo biloba: Aspirin - Simple analgesics and antipyretics

Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia

Ginkgo biloba: Bupivacaine - Anaesthetics- local and general

Retrobulbar haemorrhage associated with chronic Ginkgo biloba ingestion

Ginkgo biloba: Chlorzoxazone - CYP2E1 substrates

Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans

Clinical Assessment of Effects of Botanical Supplementation on Cytochrome P450 Phenotypes in the Elderly

Ginkgo biloba: Cilostazol - Anticoagulants, antithrombotics

Ginkgo biloba: Clopidogrel

Effect of Ginkgo Biloba Extract on the Pharmacokinetics and Metabolism of Clopidogrel in Rats.

Pharmacodynamic interaction studies of Ginkgo biloba with cilostazol and clopidogrel in healthy human subjects

Ginkgo biloba: Clopidogrel - Anticoagulants, antithrombotics

Ginkgo biloba: Diclofenac - Non-steroidal anti-inflammatory agents

Ginkgo did not affect the pharmacokinetics of diclofenac in healthy volunteers

Ginkgo biloba: Digoxin - Cardiac inotropic agents

Impact of ginkgo biloba on the pharmacokinetics of digoxin.

Ginkgo biloba: Donepezil - Other central nervous system agents

The effects of Ginkgo biloba extracts on the pharmacokinetics and pharmacodynamics of donepezil

Ginkgo biloba: Efavirenz - Antiviral agents

Interaction of Ginkgo biloba with efavirenz.

Ginkgo biloba: Esomeprazole (Nexium) - Hyperacidity, reflux and ulcers

Pharmacogenetics and herb-drug interactions: experience with Ginkgo biloba and omeprazole

Ginkgo biloba: Glipizide - Hypoglycaemic agents

The effect of 3-month ingestion of Ginkgo biloba extract (EGb 761) on pancreatic beta-cell function in response to glucose loading in individuals with non-insulin-dependent diabetes mellitus

Ginkgo biloba: Glyburide - Hypoglycaemic agents

Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects.

Ginkgo biloba: Lidocaine - Anaesthetics- local and general

Retrobulbar haemorrhage associated with chronic Ginkgo biloba ingestion

Ginkgo biloba: Metformin - Hypoglycaemic agents

Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects.

Ginkgo biloba: Nicardipine - Cardiac inotropic agents

Feeding of Ginkgo biloba extract (GBE) enhances gene expression of hepatic cytochrome P-450 and attenuates the hypotensive effect of nicardipine in rats.

Interaction of Ginkgo biloba extract (GBE) with hypotensive agent, nicardipine, in rats

Ginkgo biloba: Nifedipine - Antihypertensive agents

Studies on interactions between functional foods or dietary supplements and medicines. III. Effects of Ginkgo biloba leaf extract on the pharmacokinetics of nifedipine in rats

Studies on Interactions between Functional Foods or Dietary Supplements and Medicines. IV. Effects of Ginkgo biloba Leaf Extract on the Pharmacokinetics and Pharmacodynamics of Nifedipine in Healthy Volunteers

An open trial of nifedipine-herb interactions: Nifedipine with St. John's wort, ginseng or Ginkgo biloba

Ginkgo biloba: Omeprazole (Prilosec, Zegerid, Omesec) - Hyperacidity, reflux and ulcers

Pharmacogenetics and herb-drug interactions: experience with Ginkgo biloba and omeprazole

Ginkgo biloba: Phenytoin - Anticonvulsants

Fatal seizures due to potential herb-drug interactions with Ginkgo biloba.

Ginkgo biloba: Raltegravir - Antiviral agents

Effect of ginkgo biloba on the pharmacokinetics of raltegravir in healthy volunteers.

Ginkgo biloba: Tadalafil

Possible Drug-nutraceutical Interaction leading to Unexpected Sequelae after Inguinal Hernia Repair.

Ginkgo biloba: Talinolol

Ginkgo biloba: Ticlopidine - Anticoagulants, antithrombotics

Anti platelet and anti thrombotic effects of a combination of Ticlopidine and Ginkgo biloba ext (EGb 761)

The effects of ergoloid mesylates and ginkgo biloba on the pharmacokinetics of ticlopidine

Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: an open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers.

Ginkgo biloba: Tolbutamide - Hypoglycaemic agents

Ginkgo biloba extract modifies hypoglycemic action of tolbutamide via hepatic cytochrome P450 mediated mechanism in aged rats

Ginkgo biloba: evaluation of CYP2C9 drug interactions in vitro and in vivo

Ginkgo biloba: Trazodone - Antidepressants

Coma in a patient with Alzheimer's Disease taking low dose trazodone and Ginkgo biloba.

Ginkgo biloba: Troglitazone - Hypoglycaemic agents

The effect of 3-month ingestion of Ginkgo biloba extract (EGb 761) on pancreatic beta-cell function in response to glucose loading in individuals with non-insulin-dependent diabetes mellitus.

Ginkgo biloba: Warfarin - Anticoagulants, antithrombotics

Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.

Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial.

Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach

Korean ginseng: Antidepressants

Phenelzine and the dream machine-ramblings and reflections

Interaction of ginseng with phenelzine

Manic episode and ginseng: report of a possible case.

Korean ginseng: Hypoglycaemic agents

Null and opposing effects of Asian ginseng (Panax ginseng CA Meyer) on acute glycemia: Results of two acute dose escalation studies

Ginseng therapy in non-insulin dependent diabetic patients

Korean ginseng Adefovir dipivoxil- Antiviral agents

Effects of Complementary Combination Therapy of Korean Red Ginseng and Antiviral Agents in Chronic Hepatitis B.

Korean ginseng Digoxin Cardiac inotropic agents

Effect of Asian and Siberian ginseng on serum digoxin measurement by five digoxin immunoassays. Significant variation in digoxin-like immunoreactivity among commercial ginsengs

Korean ginseng: Imatinib - Other antineoplastic agents

Imatinib and Panax ginseng: A Potential Interaction Resulting in Liver Toxicity

Korean ginseng: Nifedipine - Antihypertensive agents

An open trial of nifedipine-herb interactions: Nifedipine with St. John's wort, ginseng or Ginkgo biloba

Korean ginseng: Warfarin - Anticoagulants, antithrombotics

Effect of St. John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects

Possible influences of ginseng on the pharmacokinetics and pharmacodynamics of warfarin in rats

Probable interaction between warfarin and ginseng

Thrombosis of a prosthetic aortic heart valve disclosing a hazardous interaction between warfarin and a commercial ginseng product

Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach

Inconclusive -

Ginkgo biloba: Amikacin - Aminoglycosides

Amikacin ototoxicity enhanced by Ginkgo biloba extract (EGb 761)

Ginkgo biloba: Bupropion - Agents used in drug dependence

Effects of Ginkgo biloba extract on the pharmacokinetics of bupropion in healthy volunteers.

Ginkgo biloba: Diltiazem - Antihypertensive agents

Studies on interactions between functional foods or dietary supplements and medicines. I. Effects of Ginkgo biloba leaf extract on the pharmacokinetics of diltiazem in rats

Ginkgo biloba: Metformin - Hypoglycaemic agents

The efficacy and safety of Ginkgo biloba extract as an adjuvant in type 2 diabetes mellitus patients ineffectively managed with metformin: a double-blind, randomized, placebo-controlled trial.

Ginkgo biloba: Phenobarbitone - Anticonvulsants

Pretreatment with Ginkgo biloba extract weakens the hypnosis action of phenobarbital and its plasma concentration in rats

Ginkgo biloba: Voriconazole - Antifungal agents

Lack of effect of Ginkgo biloba on voriconazole pharmacokinetics in Chinese volunteers identified as CYP2C19 poor and extensive metabolizers.

Korean ginseng: Topical corticosteroids

Ginsenoside Rg1 down-regulates glucocorticoide receptor and displays synergistic effects with cAMP

Korean ginseng: Albendazole - Anthelmintics

Ginseng increases intestinal elimination of albendazole sulfoxide in the rat