ThyroPlex features a blend of nutrients, including iodine, which supports healthy thyroid gland function, plus the herbs bupleurum and schisandra. The nutrients iodine and selenium assist in the healthy production of thyroid hormones. Selenium, zinc and vitamins E and C are antioxidants that reduce free radicals formed in the body. Zinc and vitamins C, A and D also help maintain healthy immune system function.

• Schisandra chinensis (schisandra) fruit 187.5 mg (equiv. to dry 750 mg)
• Bupleurum falcatum (bupleurum) root 50 mg (equiv. to dry 500 mg)
• Tyrosine 500 mg
• Ascorbic acid (vitamin C) 50 mg
• Glutathione (reduced) - Setria 25 mg
• d-alpha tocopheryl acid succinate 10.3 mg (equiv. to vitamin E 12.5 IU)
• Zinc (as amino acid chelate) 10 mg
• Retinol acetate 431 mcg equiv. to vitamin A (375 mcg retinol equivalents)
• Iodine (as potassium iodide) 145 micrograms
• Selenium (as selenomethionine) 75 micrograms
• Colecalciferol (vitamin D3) - Quali-D 7.5 micrograms (equiv. to vitamin D3 300 IU)

Adults: Take 1 tablet two times a day, or as professionally prescribed.

If you are pregnant, or considering becoming pregnant, do not take vitamin A supplements without consulting your doctor or pharmacist. When taken in excess of 3000 micrograms retinol equivalents, vitamin A can cause birth defects.

The recommended daily amount of vitamin A from all sources is 700 micrograms retinol equivalents for women and 900 micrograms retinol equivalents for men.

Do not use during pregnancy or breastfeeding.

Adults only.

This product contains selenium which is toxic in high doses. A daily dose of 150 micrograms for adults of selenium from dietary supplements should not be exceeded.

Avoid combination -

Iodine: Amiodarone - Antiarrhythmic agents

Amiodarone. Australian Medicines Handbook 2011 (online).

Schisandra: Midazolam - Sedatives, hypnotics

Effects of Schisandra sphenanthera extract on the pharmacokinetics of midazolam in healthy volunteers.

Effects of short-term and long-term pretreatment of Schisandra lignans on regulating hepatic and intestinal CYP3A in rats.

Schisandra: Sirolimus - Immunomodifiers

A study about drug combination therapy of Schisandra sphenanthera extract and Rapamycin in healthy subjects.

Vitamin A: Acitretin - Acne, keratolytics and cleansers

TGA Online Product Information: Acitretin

Vitamin A: Isotretinoin - Acne, keratolytics and cleansers

TGA Online Product Information: Isotretinoin

Zinc: Demeclocycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Zinc: Minocycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Zinc: Norfloxacin - Quinolones

Norfloxacin interaction with antacids and minerals.

Zinc: Tetracycline - Tetracyclines

Effect of zinc sulphate on the absorption of tetracycline and doxycycline in man.

Caution -

Iodine: Lithium - Antipsychotic agents

Iodine and lithium-induced hypothyroidism. Documentation of synergism.

Schisandra: CYP3A4 substrates

Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract.

A study about drug combination therapy of Schisandra sphenanthera extract and Rapamycin in healthy subjects.

Effects of Schisandra sphenanthera extract on the pharmacokinetics of midazolam in healthy volunteers.

Schisandra: P-glycoprotein substrates

Schisandrin B - a novel inhibitor of P-glycoprotein

Effect of Schisandra chinensis extract and Ginkgo biloba extract on the pharmacokinetics of talinolol in healthy volunteers.

Effect of Schisandra chinensis extract and Ginkgo biloba extract on the pharmacokinetics of talinolol in healthy volunteers.

Schisandra: Talinolol - Beta-adrenergic blocking agents

Selenium: Warfarin - Anticoagulants, antithrombotics

Modification of the effects of aflatoxin B1 and warfarin in young pigs given selenium.

Vitamin C: Indinavir - Antiviral agents

Effect of high-dose vitamin C on the steady-state pharmacokinetics of the protease inhibitor indinavir in healthy volunteers.

Vitamin C: Propranolol - Beta-adrenergic blocking agents

Influence of vitamin C on the absorption and first pass metabolism of propranolol.

Vitamin C: Warfarin - Anticoagulants, antithrombotics

Possible warfarin resistance due to interaction with ascorbic acid: Case report and literature review

Vitamin D (Cholecalciferol): Chemotherapeutic agents

A prospective clinical trial of cholecalciferol 2000 IU/day in colorectal cancer patients: evidence of a chemotherapy-response interaction.

Vitamin D (Cholecalciferol): Sirolimus - Immunomodifiers

Seasonal variation in blood drug concentrations and a potential relationship to vitamin D.

Vitamin E: Warfarin - Anticoagulants, antithrombotics

Risk of mortality with vitamin E supplements: the Cache County study.

The effect of vitamin E on warfarin-induced vitamin K deficiency.

Effect of vitamin E on the anticoagulant response to warfarin.

Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials.

Zinc: Cephalexin - Cephalosporins

The Effect of Staggered Administration of Zinc Sulfate on the Pharmacokinetics of Oral Cephalexin

Zinc: Penicillamine - Antirheumatoid agents

Treatment of Wilson's disease with zinc: XI. Interaction with other anticopper agents.

Controlled trial of D-penicillamine in rheumatoid arthritis. Dose effect and the role of zinc.