A high potency vitamin B complex with additional antioxidants, vitamins and minerals. With chromium to assist with glucose metabolism, zinc to support cognitive function and vitamins B1, B2, B3, B5, B6 and B12 to support energy levels and energy production. This multivitamin and mineral formulation is useful when dietary intake is inadequate and with vitamin B5 to support a healthy stress response in the body.

Vitamins C and E and selenium are antioxidants that help to reduce free radical damage.

Chromium assists with glucose metabolism.

Vitamins B1, B2, B3, B5, B6 and B12 support energy levels and energy production.

Biotin, zinc and vitamin A support skin health.

Vitamins B1, B2, B6 and B12 support nervous system function.

Zinc supports cognitive function.

Multi Essentials contains ingredients that support general health and wellbeing.

Vitamin B5 supports a healthy stress response in the body.

• Betacarotene 4 mg
• Ascorbic acid (vitamin C) 100 mg
• d alpha tocopheryl acid succinate 82.6 mg (equiv. to vitamin E 100 IU)
• Tocopherols concentrate mixed (low alpha type) 14.7 mg
• Retinol acetate 431.2 micrograms equiv. to vitamin A (375 micrograms retinol equivalents)
• Thiamine hydrochloride (vitamin B1) 50 mg
• Riboflavin (vitamin B2) 50 mg
• Nicotinamide (vitamin B3) 200 mg
• Pyridoxine hydrochloride 50 mg (equiv. to pyridoxine (vitamin B6) 41.1 mg)
• Cyanocobalamin (vitamin B12) 400 micrograms
• Folic acid (vitamin B9) 400 micrograms
• Biotin 100 micrograms
• Colecalciferol 1.5 micrograms (equiv. to vitamin D3 100 IU)
• Phytomenadione (vitamin K1) 30 micrograms
• Calcium pantothenate 100 mg (equiv. to pantothenic acid (vitamin B5) 91.6 mg, equiv. to calcium 8.39 mg)
• Calcium (as citrate) 50 mg
• Boron (as borax) 1 mg
• Chromium (as nicotinate) 50 micrograms
• Copper (as copper gluconate) 200 micrograms
• Magnesium (as oxide) 25 mg
• Manganese (as amino acid chelate) 1 mg
• Molybdenum (as molybdenum trioxide) 75 micrograms
• Selenium (as selenomethionine) 26 micrograms
• Zinc (as amino acid chelate) 10 mg
• Citrus bioflavonoids 50 mg
• Choline bitartrate 50 mg (equiv. to choline 20 mg)
• Inositol (myo inositol) 50 mg

Adults: Take 1 tablet once a day, or as professionally prescribed.

If you are pregnant or considering becoming pregnant, do not take vitamin A supplements without consulting your doctor or pharmacist. When taken in excess of 3000 micrograms retinol equivalents, vitamin A can cause birth defects. The recommended daily amount of vitamin A from all sources is 700 micrograms retinol equivalents for women and 900 micrograms retinol equivalents for men.

Stop taking this medication if you experience tingling, burning or numbness and see your healthcare practitioner as soon as possible [contains vitamin B6].

This product contains selenium which is toxic in high doses. A daily dose of 150 micrograms for adults of selenium from dietary supplements should not be exceeded.

Contains ethanol no more than 3% v/v as a preservative and sulfites.

Do not use during pregnancy and breastfeeding.

Avoid combination -

Calcium: Alendronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Alendronate

Calcium: Ceftriaxone - Cephalosporins

FDA Information for Healthcare Professionals: Ceftriaxone (21/4/2009)

Calcium: Ciprofloxacin - Quinolones

The influence of chronic administration of calcium carbonate on the bioavailability of oral ciprofloxacin.

Effects of aluminum hydroxide and calcium carbonate antacids on the bioavailability of ciprofloxacin.

Interference of dairy products with the absorption of ciprofloxacin.

Effect of multiple staggered doses of calcium on the bioavailability of ciprofloxacin.

Calcium: Clodronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Clodronate

Calcium: Demeclocycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Calcium: Dolutegravir

Pharmacokinetics of dolutegravir when administered with mineral supplements in healthy adult subjects.

Calcium: Doxycycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Calcium: Etidronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Etidronate

Calcium: Ibandronic acid - Agents affecting calcium and bone metabolism

TGA Online Product Information: Ibandronic acid

Calcium: Minocycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Absorption of minocycline hydrochloride and tetracycline hydrochloride. Effect of food, milk, and iron.

Calcium: Norfloxacin - Quinolones

Inhibition of norfloxacin absorption by antacids.

Inhibition of norfloxacin absorption by dairy products.

Pharmacokinetic interactions of norfloxacin with some metallic medicinal agents.

Calcium:Risedronate-Agents affecting calcium and bone metabolism

TGA Online Product Information: Risedronate

Calcium: Tetracycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Calcium: Tiludronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Tiludronate

Skelid (tiludronate disodium) Prescribing Information.

Magnesium: Alendronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Alendronate

Magnesium: Ciprofloxacin - Quinolones

Reduced enteral absorption of ciprofloxacin in the presence of antacids.

Magnesium:Clodronate-Agents affecting calcium and bone metabolism

TGA Online Product Information: Clodronate

Magnesium: Demeclocycline - Tetracyclines

Influence of ranitidine, pirenzepine, and aluminum magnesium hydroxide on the bioavailability of various antibiotics, including amoxicillin, cephalexin, doxycycline, and amoxicillin-clavulanic acid.

Magnesium: Doxycycline - Tetracyclines

Influence of ranitidine, pirenzepine, and aluminum magnesium hydroxide on the bioavailability of various antibiotics, including amoxicillin, cephalexin, doxycycline, and amoxicillin-clavulanic acid.

Magnesium: Etidronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Etidronate

Magnesium: Ibandronic acid - Agents affecting calcium and bone metabolism

TGA Online Product Information: Ibandronic acid

Magnesium: Minocycline - Tetracyclines

Influence of ranitidine, pirenzepine, and aluminum magnesium hydroxide on the bioavailability of various antibiotics, including amoxicillin, cephalexin, doxycycline, and amoxicillin-clavulanic acid.

Magnesium: Moxifloxacin - Quinolones

Evaluation of the influence of antacids and H2 antagonists on the absorption of moxifloxacin after oral administration of a 400mg dose to healthy volunteers.

Magnesium: Norfloxacin - Quinolones

Norfloxacin interaction with antacids and minerals.

Pharmacokinetic interactions of norfloxacin with some metallic medicinal agents.

Magnesium: Penicillamine - Antirheumatoid agents

Reduction in oral penicillamine absorption by food, antacid, and ferrous sulfate.

Magnesium: Proguanil - Antimalarials

The effect of magnesium trisilicate on proguanil absorption.

Magnesium: Risedronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Risedronate

Magnesium: Tetracycline - Tetracyclines

Influence of ranitidine, pirenzepine, and aluminum magnesium hydroxide on the bioavailability of various antibiotics, including amoxicillin, cephalexin, doxycycline, and amoxicillin-clavulanic acid.

Magnesium: Tiludronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Tiludronate

Skelid (tiludronate disodium) Prescribing Information.

Niacin: Warfarin - Anticoagulants, antithrombotics

Critically elevated INR in a patient on warfarin after increase in extended-release niacin dose

Vitamin A: Acitretin- Acne, keratolytics and cleansers

TGA Online Product Information: Acitretin

Vitamin A: Isotretinoin - Acne, keratolytics and cleansers

TGA Online Product Information: Isotretinoin

Vitamin K: Warfarin - Anticoagulants, antithrombotics

Over-the-counter vitamin K1-containing multivitamin supplements disrupt warfarin anticoagulation in vitamin K1-depleted patients. A prospective, controlled trial.

Effect of vitamin K intake on the stability of oral anticoagulant treatment: dose-response relationships in healthy subjects.

Australian Medicines Handbook 2011 - Warfarin and Vitamin K

Zinc: Demeclocycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Zinc: Minocycline - Tetracyclines

Interactions with the absorption of tetracyclines.

Zinc: Norfloxacin - Quinolones

Norfloxacin interaction with antacids and minerals.

Zinc: Tetracycline - Tetracyclines

Effect of zinc sulphate on the absorption of tetracycline and doxycycline in man.

Caution -

Beta-carotene: Colchicine - Agents used in gout and hyperuraecimia

Intestinal malabsorption induced by oral colchicine. Comparison with neomycin and cathartic agents.

Beta-carotene: Orlistat - Anorectics and weight reducing agents

The effect of orlistat, an inhibitor of dietary fat absorption, on the pharmacokinetics of beta-carotene in healthy volunteers.

Calcium: Sotalol - Beta-adrenergic blocking agents

Effect of food, food constituents and fluid volume on the bioavailability of sotalol.

Calcium: Thyroxine - Thyroid hormones and antithyroid agents

Calcium carbonate and reduction of levothyroxine efficacy.

Effect of calcium carbonate on the absorption of levothyroxine.

Chromium: Thyroxine - Thyroid hormones and antithyroid agents

New medications which decrease levothyroxine absorption.

Folate: Phenytoin - Anticonvulsants

Influence of folic acid on blood-phenytoin levels.

Phenytoin and folic acid interaction: a preliminary report.

Phenytoin and folic acid: individualized drug-drug interaction.

Folic acid improves phenytoin pharmacokinetics.

Phenytoin-folic acid interaction.

Folate: Warfarin - Anticoagulants, antithrombotics

Effects of folic acid supplementation on the pharmacokinetics and anticoagulant effect of warfarin: an open-label, prospective study of long-term administration in adults.

Magnesium: Amikacin - Aminoglycosides

Potentiation of magnesium sulfate-induced neuromuscular weakness by gentamicin, tobramycin, and amikacin.

Magnesium: Chlorpromazine - Antipsychotic agents

Chlorpromazine: effects of antacids on its gastrointestinal absorption.

Magnesium: Gentamicin - Aminoglycosides

Potentiation of magnesium sulfate-induced neuromuscular weakness by gentamicin, tobramycin, and amikacin.

Magnesium: Nitrofurantoin - Other antibiotics and anti-infectives

Effect of magnesium trisilicate on nitrofurantoin absorption.

Magnesium: Tobramycin - Aminoglycosides

Potentiation of magnesium sulfate-induced neuromuscular weakness by gentamicin, tobramycin, and amikacin.

Selenium: Warfarin - Anticoagulants, antithrombotics

Modification of the effects of aflatoxin B1 and warfarin in young pigs given selenium.

Vitamin B6: Levodopa - Movement disorders

Pyridoxine reversal of L-dopa effects in Parkinsonism.

Failure of vitamin B6 to reverse the L-dopa effect in patients on a dopa decarboxylase inhibitor.

Vitamin B6: Phenobarbitone - Anticonvulsants

Pyridoxine and serum concentration of phenytoin and phenobarbitone.

Vitamin B6: Phenytoin- Anticonvulsants

Pyridoxine and serum concentration of phenytoin and phenobarbitone.

Vitamin C;Indinavir - Antiviral agents

Effect of high-dose vitamin C on the steady-state pharmacokinetics of the protease inhibitor indinavir in healthy volunteers.

Vitamin C: Propranolol- Beta-adrenergic blocking agents

Influence of vitamin C on the absorption and first pass metabolism of propranolol.

Vitamin C: Warfarin - Anticoagulants, antithrombotics

Possible warfarin resistance due to interaction with ascorbic acid: Case report and literature review

Vitamin D (Cholecalciferol): Chemotherapeutic agents

A prospective clinical trial of cholecalciferol 2000 IU/day in colorectal cancer patients: evidence of a chemotherapy-response interaction.

Vitamin D (Cholecalciferol): Sirolimus - Immunomodifiers

Seasonal variation in blood drug concentrations and a potential relationship to vitamin D.

Vitamin E: Warfarin - Anticoagulants, antithrombotics

Risk of mortality with vitamin E supplements: the Cache County study.

The effect of vitamin E on warfarin-induced vitamin K deficiency.

Effect of vitamin E on the anticoagulant response to warfarin.

Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials.

Zinc: Cephalexin - Cephalosporins

The Effect of Staggered Administration of Zinc Sulfate on the Pharmacokinetics of Oral Cephalexin

Zinc: Penicillamine - Antirheumatoid agents

Treatment of Wilson's disease with zinc: XI. Interaction with other anticopper agents.

Controlled trial of D-penicillamine in rheumatoid arthritis. Dose effect and the role of zinc.