LivProtect contains traditionally used herbs to support healthy liver function. Milk thistle and globe artichoke have been traditionally used in western herbal medicine (WHM) to enhance liver health and protect the liver. Globe artichoke is used traditionally in WHM to promote bile flow from the liver, support healthy digestion and reduce the symptoms of indigestion.

• Silybum marianum (milk thistle) fruit 180 mg (min. equiv. to dry 7.2 g, std. to flavanolignans calculated as silybin 144 mg)
• Cynara scolymus (globe artichoke) leaf 80 mg (min. equiv. to dry 4 g, std. to caffeoylquinic acids calculated as cynarin 4 mg)
• Bupleurum falcatum (bupleurum) root 20 mg (equiv. to dry 200 mg)
• Glutathione (reduced) - Setria 20 mg

Adults: Take 1 tablet two to three times a day, or as professionally prescribed.

Do not use during pregnancy or breastfeeding.

Adults only.

Avoid combination -

Artichoke: Colchicine

Case Report: Severe Hematological, Muscle and Liver Toxicity Caused by Drugs and Artichoke Infusion Interaction in an Elderly Polymedicated Patient

St Mary's thistle: Atorvastatin - HMG-CoA reductase inhibitors (statins)

An unwanted complement: Rare case of potential liver injury induced by an interaction between ginseng and atorvastatin.

Caution -

St Mary's thistle: Darunavir/Ritonavir - Antiviral agents

Effect of Milk Thistle on the Pharmacokinetics of Darunavir-Ritonavir in HIV-Infected Patients.

St Mary's thistle: Daunorubicin - Antibiotic cytotoxics

Effect of flavonoids on MRP1-mediated transport in Panc-1 cells

St Mary's thistle: Doxorubicin - Antibiotic cytotoxics

Antiproliferative effect of silybin on gynaelogical malignancies: synergism with cisplatin and doxorubicin

St Mary's thistle: Indinavir - Antiviral agents

Coadministration of milk thistle and indinavir in healthy subjects

Effect of milk thistle on the pharmacokinetics of indinavir in healthy volunteers

Use of herbal products and potential interactions in patients with cardiovascular diseases

Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis

St Mary's thistle: Irinotecan - Other antineoplastic agents

Effect of Milk Thistle (Silybum marianum) on the Pharmacokinetics of Irinotecan

St Mary's thistle: Metronidazole - Other antibiotics and anti-infectives

Study on the influence of silymarin pretreatment on metabolism and disposition of metronidazole

St Mary's thistle: Risperidone - Antipsychotic agents

Effects of single or repeated silymarin administration on pharmacokinetics of risperidone and its major metabolite, 9-hydroxyrisperidone in rats.

St Mary's thistle: Vinblastine - Vinca alkaloids

Effect of flavonoids on MRP1-mediated transport in Panc-1 cells

Effect of the Flavonoids Biochanin A and Silymarin on the P-Glycoprotein-Mediated Transport of Digoxin and Vinblastine in Human Intestinal Caco-2 Cells.

Inconclusive -

St Mary's thistle: Digoxin - Cardiac inotropic agents

Effect of the Flavonoids Biochanin A and Silymarin on the P-Glycoprotein-Mediated Transport of Digoxin and Vinblastine in Human Intestinal Caco-2 Cells.

St Mary's thistle does not affect the pharmacokinetics of digoxin in healthy volunteers.