Ultra Muscleze Cream contains magnesium, menthol and wintergreen oil in a paraben-free, topical cream. Magnesium supports healthy muscle contraction function and supports muscle relaxation. Ultra Muscleze Cream helps to maintain magnesium levels in the body.

• Magnesium (as magnesium chloride hexahydrate) 167 mg (equiv. to magnesium 20 mg)
• Wintergreen oil 1 mg (equiv. to methyl salicylate 940 micrograms)
• Mentha arvensis (field mint) essential oil 1 mg (equiv. to menthol 700 micrograms)

Adults: Massage 5 g (approx. 1 metric teaspoon) to the affected area(s) up to three times a day, or as professionally prescribed. Do not use on damaged or broken skin. Each 5 g contains 100 mg elemental magnesium.

Avoid use in pregnancy and lactation.

Wintergreen essential oil is contraindicated in pregnancy and lactation.

Concomitant use of topical wintergreen oil-containing products and warfarin can increase INR levels and bleeding risk due to systemic absorption of the methyl salicylate in wintergreen oil.

Topical use of wintergreen oil in large amounts, with occlusive dressings or for prolonged periods of time, can cause additive salicylate toxicity.

Individuals with salicylate allergy, asthma or nasal polyps should use wintergreen cautiously due to its potential for allergic reaction.

Avoid combination -

Magnesium: Alendronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Alendronate

Magnesium: Ciprofloxacin - Quinolones

Reduced enteral absorption of ciprofloxacin in the presence of antacids.

Magnesium: Clodronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Clodronate

Magnesium: Demeclocycline - Tetracyclines

Influence of ranitidine, pirenzepine, and aluminum magnesium hydroxide on the bioavailability of various antibiotics, including amoxicillin, cephalexin, doxycycline, and amoxicillin-clavulanic acid.

Magnesium: Doxycycline - Tetracyclines

Influence of ranitidine, pirenzepine, and aluminum magnesium hydroxide on the bioavailability of various antibiotics, including amoxicillin, cephalexin, doxycycline, and amoxicillin-clavulanic acid.

Magnesium: Etidronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Etidronate

Magnesium: Ibandronic acid - Agents affecting calcium and bone metabolism

TGA Online Product Information: Ibandronic acid

Magnesium: Minocycline - Tetracyclines

Influence of ranitidine, pirenzepine, and aluminum magnesium hydroxide on the bioavailability of various antibiotics, including amoxicillin, cephalexin, doxycycline, and amoxicillin-clavulanic acid.

Magnesium: Moxifloxacin - Quinolones

Evaluation of the influence of antacids and H2 antagonists on the absorption of moxifloxacin after oral administration of a 400mg dose to healthy volunteers.

Magnesium: Norfloxacin - Quinolones

Norfloxacin interaction with antacids and minerals.

Pharmacokinetic interactions of norfloxacin with some metallic medicinal agents.

Magnesium: Penicillamine - Antirheumatoid agents

Reduction in oral penicillamine absorption by food, antacid, and ferrous sulfate.

Magnesium: Proguanil - Antimalarials

The effect of magnesium trisilicate on proguanil absorption.

Magnesium: Risedronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Risedronate

Magnesium: Tetracycline - Tetracyclines

Influence of ranitidine, pirenzepine, and aluminum magnesium hydroxide on the bioavailability of various antibiotics, including amoxicillin, cephalexin, doxycycline, and amoxicillin-clavulanic acid.

Magnesium: Tiludronate - Agents affecting calcium and bone metabolism

TGA Online Product Information: Tiludronate

Skelid (tiludronate disodium) Prescribing Information.

Caution -

Magnesium: Amikacin - Aminoglycosides

Potentiation of magnesium sulfate-induced neuromuscular weakness by gentamicin, tobramycin, and amikacin.

Magnesium: Chlorpromazine - Antipsychotic agents

Chlorpromazine: effects of antacids on its gastrointestinal absorption.

Magnesium: Gentamicin - Aminoglycosides

Potentiation of magnesium sulfate-induced neuromuscular weakness by gentamicin, tobramycin, and amikacin.

Magnesium: Nitrofurantoin - Other antibiotics and anti-infectives

Effect of magnesium trisilicate on nitrofurantoin absorption.

Magnesium: Tobramycin - Aminoglycosides

Potentiation of magnesium sulfate-induced neuromuscular weakness by gentamicin, tobramycin, and amikacin.

Peppermint: Substrates of multiple CYP enzyme subtypes

Effect of herbal teas on hepatic drug metabolizing enzymes in rats

Peppermint: Cyclosporin - Immunomodifiers

Peppermint Oil Enhances Cyclosporine Oral Bioavailability in Rats: Comparison With D-alpha-Tocopherol Poly(ethylene glycol 1000) Succinate (TPGS) and Ketoconazole.

Peppermint: Felodipine - Antihypertensive agents

Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo.