Mega B Q10 contains the bioavailable and metabolically active forms of vitamin B2, B6 and B9, plus CoQ10 to help maintain energy levels. Vitamin E and CoQ10 are antioxidants that reduce free radicals formed in the body. Vitamins B1, B6 and B12 support nervous system function and vitamin B5 supports a healthy stress response in the body. A comprehensive formula in a convenient one-a-day capsule.

• Thiamine nitrate 61.7 mg (equiv to. thiamine (vitamin B1) 50 mg)
• Riboflavin sodium phosphate (active vitamin B2) 68.5 mg (equiv. to riboflavin (vitamin B2) 50 mg)
• Nicotinamide (vitamin B3) 90 mg
• Nicotinic acid (vitamin B3) 10 mg
• Calcium pantothenate 49.1 mg (equiv. to pantothenic acid (vit B5) 45 mg)
• Pyridoxal-5-phosphate monohydrate (P5P) (active vitamin B6) 15.7 mg (equiv. to pyridoxine (vitamin B6) 10 mg)
• Pyridoxine hydrochloride 48.6 mg (equiv. to pyridoxine (vitamin B6) 40 mg)
• Calcium folinate 556 micrograms (equiv. to folinic acid (activated vitamin B9) 400 micrograms)
• Cyanocobalamin (vitamin B12) 400 micrograms
• Retinol palmitate 824.7 micrograms (equiv. to vitamin A 450 micrograms retinol equivalents)
• Colecalciferol (vitamin D3) 25 micrograms (equiv. to vitamin D3 1000 IU)
• d-alpha-tocopherol acetate (Vit E 15 IU) 16.8 mg (equiv. to vitamin E 25 IU)
• Biotin 300 micrograms
• Ubidecarenone (co-enzyme Q10) 30 mg

Adults: Take 1 capsule once a day, or as professionally prescribed. Take with food.

If you are pregnant or considering becoming pregnant, do not take vitamin A supplements without consulting your doctor or pharmacist. When taken in excess of 3000 micrograms retinol equivalents, vitamin A can cause birth defects.

The recommended daily amount of vitamin A from all sources is 700 micrograms retinol equivalents for women and 900 micrograms retinol equivalents for men.

If you are pregnant or breastfeeding, talk to your health professional before use.

Do not take while on warfarin therapy without medical advice.

Contains soya bean products and sulfites.

People with cancer, anxiety or narcolepsy should talk to their doctors before taking vitamin B6; it may interact with their medications.

Vitamin B6 should not be used in high doses (>100 mg) long-term, as this can induce toxicity.

Concurrent use of anti-seizure medications with vitamin B6 should be monitored.

Vitamin B6 is commonly used to reduce symptoms of morning sickness, but may interact with other anti-nausea medicines for pregnancy.

Women who are pregnant or breastfeeding should talk to their doctor before taking vitamin A.

It is not recommended to take large amounts during pregnancy.

Less than 10,000 IU (3000 micrograms) per day is considered safe in pregnancy and lactation.

Adjunctive use of tetracycline antibiotics with vitamin A may increase side-effects and should be avoided.

People with liver or renal disease, alcoholism or severe osteoporosis should use vitamin A supplements with caution.

People with hypercalcaemia should not take vitamin D; it will worsen symptoms.

Vitamin D is not to be taken in sarcoidosis or hyperparathyroidism without medical supervision.

Observe patients on warfarin taking CoQ10 dosing higher than 100 mg.

Theoretically, vitamin B3 may have additive effects when used with anticoagulant or antiplatelet drugs, especially in patients on haemodialysis.7

Avoid combination -

Niacin: Warfarin - Anticoagulants, antithrombotics

Critically elevated INR in a patient on warfarin after increase in extended-release niacin dose

Vitamin A: Acitretin - Acne, keratolytics and cleansers

TGA Online Product Information: Acitretin

Vitamin A: Isotretinoin - Acne, keratolytics and cleansers

TGA Online Product Information: Isotretinoin

Caution -

Coenzyme Q10: Warfarin - Anticoagulants, antithrombotics

Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial

Risk of warfarin-related bleeding events and supratherapeutic international normalized ratios associated with complementary and alternative medicine: a longitudinal analysis

Folate: Phenytoin - Anticonvulsants

Influence of folic acid on blood-phenytoin levels.

Phenytoin and folic acid interaction: a preliminary report.

Phenytoin and folic acid: individualized drug-drug interaction.

Folic acid improves phenytoin pharmacokinetics.

Phenytoin-folic acid interaction.

Folate: Warfarin - Anticoagulants, antithrombotics

Effects of folic acid supplementation on the pharmacokinetics and anticoagulant effect of warfarin: an open-label, prospective study of long-term administration in adults.

Vitamin B6: Levodopa - Movement disorders

Pyridoxine reversal of L-dopa effects in Parkinsonism.

Failure of vitamin B6 to reverse the L-dopa effect in patients on a dopa decarboxylase inhibitor.

Vitamin B6: Phenobarbitone - Anticonvulsants

Pyridoxine and serum concentration of phenytoin and phenobarbitone.

Vitamin B6: Phenytoin - Anticonvulsants

Pyridoxine and serum concentration of phenytoin and phenobarbitone.

Vitamin D (Cholecalciferol) - Chemotherapeutic agents

A prospective clinical trial of cholecalciferol 2000 IU/day in colorectal cancer patients: evidence of a chemotherapy-response interaction.

Vitamin D (Cholecalciferol): Sirolimus - Immunomodifiers

Seasonal variation in blood drug concentrations and a potential relationship to vitamin D.

Vitamin E: Warfarin - Anticoagulants, antithrombotics

Risk of mortality with vitamin E supplements: the Cache County study.

The effect of vitamin E on warfarin-induced vitamin K deficiency.

Effect of vitamin E on the anticoagulant response to warfarin.

Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials.